Tanzania Mainland champions Young Africans (Yanga) have been drawn in Group B, while their traditional rivals Simba SC have landed in Group C following the CAF Champions League (CAFCL) group-stage draw held in Egypt.
The draw placed Tanzania's two football giants in separate groups, with each facing stiff competition as they seek to secure qualification for the quarter-finals.
Yanga in Group B Alongside Zamalek
Yanga have been drawn in Group B alongside Tunisia's Club Africain, Algeria's MC Alger and Egypt's Zamalek.
The group is expected to be highly competitive given the history and experience of these teams in African football competitions.
For Yanga, the quest to reach the quarter-finals will require strong results in both home and away matches against their three opponents.
Simba in Group C with Orlando Pirates and RS Berkane
Meanwhile, Simba SC, the Msimbazi Reds, have been drawn in Group C alongside South Africa's Orlando Pirates, Morocco's RS Berkane and Cameroon's Colombe.
The group brings Simba up against opponents, some of whom they have previously faced in African club competitions.
Simba will have the opportunity to face Orlando Pirates again, having met the South African side in the CAF Confederation Cup (CAFCC) quarter-finals three seasons ago.
They will also meet RS Berkane, whom they faced in the CAF Confederation Cup final one season ago, making this one of the fixtures likely to attract considerable attention from fans.
The other team in the group is Cameroon's Colombe, which, according to the information provided, has never previously competed at this group stage.
All CAF Champions League Groups
Here are the four groups confirmed following the conclusion of the draw:
Group A
Wiliete SC
Nouadhibou
Petro Atlético
Espérance de Tunis
Group B
Club Africain
MC Alger
Young Africans (Yanga)
Zamalek
Group C
Colombe
Orlando Pirates
Simba SC
RS Berkane
Group D
MAS de Fès
Horoya AC
Al Hilal
Pyramids FC
